Dear Colleague, <br/> <br/> It is our great pleasure to invite you to the "II. International Conference on Mathematics and its Applications in Science and Engineering (ICMASE-2021)". The conference organization committee would like to announce that it is decided to organize the ICMASE-2021 via ONLINE within the cautions of Covid-19 outbreak. <br/> <br/> This meeting aims to stimulate research and interaction of mathematicians in all aspects related to pure and applied Mathematics/Mathematics Education. Authors are invited to submit their abstracts on the related, but not limited, following topics of their research area: Applied Mathematics, Algebra and Number Theory, Analysis, Geometry, Statistics, Mathematics Education, Computational Mathematics, Discrete Mathematics. <br/> <br/> The presentations will be given in English. <br/> <br/> The peer-reviewed abstracts of all accepted presentations will be published in the conference abstracts book. <br/> <br/> The sessions will NOT be registered. <br/> <br/> Time schedule is respect to Spain time zone <br/> <br/> This meeting will be held via ZOOM. <br/> <br/> We look forward to seeing you virtually for ICMASE 2021 between 1-2 July 2021.